Feed additives are a large family. Although the amount of livestock body demand is relatively small, the effect is rather large. Members of this family have different chemical structures, nutritional effects, and physiological effects. Among them, vitamin d3 is undoubtedly one of the most eye-catching stars. As a new green feed additive, feed grade vitamin d3 has been widely used in the feed industries.
Here is the content list:
What metabolic pathway does vitamin d3 go through in livestock?
What are the functions of vitamin d3 in regulating livestock physiology?
What is the nutritional value of vitamin d3 to livestock?
What metabolic pathway does vitamin d3 go through in livestock?
Before figuring out how vitamin d3 works, we need to understand how vitamin d3 is digested. Vitamin d3 feed additive ingested from feed is absorbed by the intestine in the presence of bile salts and fat, and passively diffuses into the intestinal cells.
No matter being absorbed through the small intestine or synthesized by skin photosynthesis, it must first be transported to the liver through a specific DBP. Vitamin d3 powder is dehydrogenated under the action of 25-hydroxylase in hepatocyte microsomes and mitochondria, which will be called as 25(OH)D3.
Subsequently, vitamin d3 converted into 25(OH)D3 enters the kidney. Under the catalysis of 1-α hydroxylase in renal tubular cell mitochondria, 25(OH)D3 is converted into the final active form, becoming the vitamin D metabolite with the greatest biological activity, and then is transported to the intestines, kidneys or other target tissues to regulate calcium and phosphorus metabolism.
What are the functions of vitamin d3 in regulating livestock physiology?
Vitamin d3 regulates many biological functions of animals, including cell growth, differentiation and the body's immune function, reproduction and reproduction, mineral metabolism and other functions. Feed grade vitamin d3 essentially exerts its physiological functions through 1,25(OH)2D3.
The most important physiological function of vitamin d3 powder is to regulate the metabolism of Ca and P in the body, especially to promote the formation of calcium binding protein in the epithelial cells of the intestinal mucosa, promote the absorption of Ca and P in the intestine, and the calcification of bones and teeth. Most of the other adjustments depend on these two functions.
In addition, the appropriate level of vitamin d3 supplementation can make the animal's immune response strong, and the antibody concentration will increase rapidly.
And when vitamin d3 is lacking in the feed, the supplementation level is too high that getting toxic, the antibody production of the heterologous protein antigen BSA will decrease. Large doses of vitamin d3 feed additives can inhibit cellular immune function and reduce the thickness of skinfolds stimulated by PHA.
What is the nutritional value of vitamin d3 to livestock?
Only when the physiological function is normal, the livestock can make good use of vitamin d3 to absorb nutrients, and the nutritional function of vitamin d3 in turn guarantees normal physiological activities. For various livestock, feed additives vitamin d3 has distinct effects.
Give the vitamin d3 mixed feeds to the laying poultry in a timely and appropriate amount, the vitamin d3 components can be effectively transferred to the eggs, so that the embryos can develop in a more stable and solid eggshell.
The vitamin d3 transformation can increase the hatching rate, thereby increasing the survival rate of young poultry and prolonging the growth cycle of egg-laying poultry. And once the young poultry matures, they will not be affected by congenital rickets and avoid leg diseases.
Relevant investigations show that the use of vitamin d3 before and after delivery of dairy cows can not only effectively prevent birth paralysis, but also reduce fetal retention, accelerate the discharge of lochia, promote uterine purification, and restore the estrus cycle earlier.
A large number of studies have found that supplementing vitamin D before slaughter can increase beef tenderness and improve pork color. This is because pre-slaughter supplementation with vitamin d3 can promote the degradation of troponin-T, destroy the structure of muscle fibers, thereby improving muscle tenderness.
Vitamin d3 has unique physiological and nutritional functions, but in fact we only discovered the tip of the iceberg. Polifar Group has produced vitamin d3 feed additives for many years, and has a variety of measures to purchase raw materials to ensure the safe production and stable supply of products. If you are interested in feed grade vitamin d3, welcome to consult our customers, we have been waiting for you.